Expanded criteria donor kidneys (ECD) have the
potential to greatly increase the number of kidneys available for
transplantation; however utilization is limited by poorer outcomes.
One strategy to improve outcomes and
secondarily utilization is improved matching of kidneys based
on recipient factors such as surface area, kidney graft size to recipient
weight and kidney weight to recipient weight.
Recently our group developed the creatinine
clearance match ratio (CCMR) as an improved matching technique. The CCMR is
calculated using a manipulation of the Cockcroft-Gault equation estimating the
creatinine clearance required by the recipient at a serum creatinine level of
1.0 thereby producing an estimated value for an individual’s creatinine
production and in intellectual shorthand, “nephron need”.
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