Osteoporosis is
characterized by low bone mass, deterioration of the bone microarchitecture and
increased bone fragility, which inevitably result in an amplified risk for
fractures.
Spinal Cord
Injury (SCI) is strongly associated with declined bone mineral density
and increased incidence of osteoporosis. This is a serious complication of
the spinal injury as the osteoporotic paralyzed limbs of the SCI patients are
vulnerable to pathological fractures even after subtle and no obvious trauma.
Bone loss in
these patients is higher in the first six months after the SCI and stabilizes
between 12 and 16 months, with about 30% loss of bone mass.
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