17-months old
infant with Wiskott-Aldrich syndrome was transplanted with genetically
two-locus mismatched unrelated cord blood cells
under the conditioning regimen of busulfan, cyclophosphamide and
anti-thymocyte globulin.
GVHD prophylaxis
was cyclosporine (CSP) plus short-term methotrexate with prednisolone (1
mg/kg). Acute and chronic GVHD were not observed during the course.
About six years
later, he suffered from severe cough and dyspnea with no fever, and diagnosed
as late onset non-infectious pulmonary complications (LONIPC).
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