Childern and young adults, who suffer from
cancer, receive gonadotoxic therapy, which destroys their fertile abilities
after survival.
Ovarian cryopreservation and transplantation
provides the promising solution to this problem, where the ovary can be removed
before the gonadotoxic
therapy and reimplanted after patient's survival, where the ovary
is to be cryopreserved during the period of the therapy.
However, cryopreservation of the whole ovary
is still facing great obstacles, namely the ischemic reperfusion injury and the
defective cryopreservation related to the defective ability to universally
deliver the cryopreservation/warming solutions through the ovarian vascular
bed.
